Exelon Patch: Less is Better

Alzheimer's and Dementia Weekly

Sometimes less is more: Lower doses of an Alzheimer’s drug delivered via skin patches improve cognition with fewer serious side effects than higher doses, researchers have found in an updated review.

The drug is rivastigmine, known in the U.S. by its brand name, Exelon.

“Is there any advantage of giving patients higher doses of rivastigmine? There doesn’t seem to be any,” said lead review author Jacqueline Birks, senior medical statistician for the University of Oxford, in England.

Previous studies had shown that high daily doses of rivastigmine (also known by its brand name, Exelon) of between 6 and 12 milligrams improved cognitive functions, such as memory, language and ability to perform simple daily living tasks, in patients with mild to moderate Alzheimer’s disease.

However, adverse events often.......read the whole story


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